Police say they responded to the collision around 10:13 a.m. Saturday at the intersection of Morris Road and Clyde Line.
A motorcycle and a pickup truck collided at the intersection and the driver of the motorcycle was taken to a hospital by ambulance, police say. They were later pronounced dead.
The deceased has been identified as 70-year-old William Gallagher of Bluevale, Ont.
OPP say Morris Road at Clyde Line was closed for several hours, but has since reopened.
Anyone with information about the crash is asked to contact Huron OPP at 1-888-310-1122 or (519) 482-1677, or Crime Stoppers at 1-800-222-TIPS (8477).
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